United made an enterprising start at the Nou Camp, with Marcus Rashford clipping the crossbar moments after kick-off, but were undone by Lionel Messi's first-half double and Philippe Coutinho's wonder strike after half-time.
'This man is insane, he doesn't need to prove himself in the prem, best of all time, no doubt.' added another.
And from there it was very much a damage limitation job for the Red Devils.
In the first two minutes at the Camp Nou, United did more than they had in 90 minutes at Old Trafford.
Messi had failed to score in his last 12 quarter-final appearances, but he settled his side's nerves after a bright start from United, collecting a misplaced pass from Ashley Young and curling into the bottom corner in the 16th minute.
"At 2-0 straight after it was game over".
Eberle, Islanders put Penguins on brink of elimination
The home crowd was silent, and then the anxiety grew 62 seconds later when Brock Nelson gave the Islanders a 2-1 lead. With 12:06 to go in the third period, Eberle broke the tie on a goal assisted by Barzal and Johnny Boychuk .
"Messi is an exceptional talent, him and Cristiano (Ronaldo) have been the best players in the world in the last decade". Messi showed his quality. "But then there were another 85 minutes where we weren't bad". When you make an error, it can get highlighted and that'll be remembered.
Manchester United are now in sixth place in the Premier League table and two points behind fourth-placed Arsenal with five games left to play this season.
They made an enterprising start as Marcus Rashford struck the top of the crossbar in the first few seconds but were thoroughly second best after five-time Ballon d'Or victor Messi opened the scoring after 16 minutes.
Asked about the challenge of taking on a player like Messi, Alvarez told Cadena Ser radio: "We do some things different".
"You have to lift them (the players)".
"We had a lot of hope for this tie, it was a long time since we have been in the semi-finals and we had a very painful defeat previous year", he said.
2 - Ajax have been eliminated on two of the three previous occasions they have drawn the first leg of a Champions League knockout tie at home, most recently in the 2005-06 last 16 against Inter Milan.
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