Lloris then faced the ultimate test as Leicester were awarded a penalty when Jan Vertonghen was adjudged to have brought down Maddison. Frustratingly for Leicester fans, those two impressive results aside, they have lost five of their last six games in all competitions, including defeats to Newport, Cardiff and Southampton.
A key turning point came on the hour when Jamie Vardy missed a penalty for Leicester with his first touch of the game.
Vardy had scored his previous seven penalties and would later reduce the arrears, but Spurs would seal the win through Heung-Min Son in stoppage time.
Son was booked in the first half after going down in the area under a challenge from Harry Maguire, becoming the fourth Spurs player to be yellow-carded for simulation this season.
Their attention now turns to the Champions League, where they host Borussia Dortmund in the last 16, though Pochettino is unhappy with the scheduling of this game against the Foxes.
Insisting he was happy for Vardy to take the penalty, Puel said: "I gave him the opportunity".
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She said Mr Cotten died from complications linked to the disease, which disrupts digestion by causing inflammation of the bowels. Cotton was diagnosed at the hospital with a case of septic shock , perforation peritonitis , and intestinal obstruction.
"Maybe it was not a good thing, but we had a lot of chances, not just with this penalty". I think we are such nice people.
Spurs though threw the first punch after Davidson Sanchez nodded home Christian Eriksen's inch-perfect cross on 33 minutes. I told Michael Oliver.
"It was the same referee but now I don't know how he has measured the situation".
Three minutes later the game took another twist as we doubled our lead when Oliver Skipp - on his second Premier League start - closed down a clearance, Llorente picked up the loose ball and laid it off for Eriksen, who drilled in right-footed from 20 yards.
It was not the first time a player has taken a spot-kick in the Premier League immediately after coming on with Wigan midfielder Ben Watson doing so on New Year's Eve in November 2011, sealing a 2-2 draw.
But Vardy partly made amends in the 76th when he turned in Pereira's cross from close range.
Still angry about the decision after the match, Pochettino fumed: "It's unbelievable".
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