The fires have have now crossed over the main coastal highway and reached the Pacific Ocean, on America's West Coast.
California Gov. Jerry Brown has declared a state of emergency in Ventura and Los Angeles counties.
"This is good news for the fire crews as the winds will not be driven quite as vigorously", a weather service statement said.
Homes there have been damaged and more than 400 firefighters have been sent there.
"We have nothing in Ventura and it's not getting better", Kirwin said.
As happened during the North Bay fires, gusting winds rapidly spread flames and struck at night when aircraft couldn't be used to battle the blazes.
Additional evacuations were called for late on Wednesday in the Ventura area, where 50,000 people had already fled their homes over the last three days.
"The danger is imminent", Cal Fire said in its evacuation notice. "Stay alert and prepared in case of evacuations".
Smoke covers Ventura Harbor in Ventura. She tried to save her neighbor's two cats but could find only one before a neighbor screamed for her to leave.
"We got knots in our stomach coming back up here", Kermode said. "It was raining fire". She got dressed, grabbed her dog, Sweetie, and corralled neighbors into her vehicle for a drive through heavy smoke to the Ventura County Fairgrounds. Red Flag warnings will remains in effect until Saturday night.
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The Thomas Fire has destroyed more than 150 homes and threatened thousands more in Ventura.
A resident hoses a burning palm tree during the Creek Fire in Sunland, California.
Below, a list of the freeway and road closures cause by the fires so far. The fire broke out in the Rye Canyon Loop and grew to 5,000 acres by Tuesday afternoon. The brush fire has charred 475 acres and is 5 percent contained.
Weather officials expect winds to pick up through Thursday, bringing "damaging" gusts of 50 to 70 miles per hour that could knock down trees and power lines, and cause fire to spread rapidly.
Interested in California Wildfires?"This is not flat land, and some areas are inaccessible to get equipment to".
Edison had taken steps to prepare for the Santa Ana winds.
"They've died down slightly, but they're going to increase again (Tuesday) evening, so it's kind of like a seesaw", McLean said.
"We are adjacent to a gas station, which many people don't like, however, in this case, we know the fire department will not let a gas station go up in flames if they can stop it, so that makes me feel a little better", she said. "It's December. We have fires all year round now".
Ventura County has been exceedingly dry in recent months. In October and November, the total was only 0.05 inches.
The flames have swallowed about 80,000 acres (32,000 hectares) in just over a day since the "Thomas" fire, now the state's largest, broke out, leaving at least one dead in an area about 45 minutes from downtown LA.
One of the wildfires may have finally met its match, though.
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