Bryant closed the half hitting 17-of-27 passes for 238 yards and a touchdown with 12 carries for 35 yards and another score.
Mississippi State earned its first win over LSU in Starkville since 1999 Saturday night.
Saturday night was a stark wake-up call for an LSU team that spent the first two games of Ed Orgeron's first season as permanent head coach blasting an 0-3 Independent (Brigham Young) and an FCS opponent (Chattanooga) and had risen to No. 2 in Football Outsiders' S&P + ratings. None of Louisville's four possessions after the touchdown lasted longer than five plays, and Jackson was limited to 7-of-19 passing for 72 yards and a score with six carries for 55 yards.
LSU's lone score came on Darrel Williams' 10-yard TD run in the first quarter, which made the score 7-7.
Quarterback Danny Etling was 13-of-29 for 137 yards, as a few of his passes were dropped.
D'Tigers overcome Senegal, set up AfroBasket Final withTunisia
Diogu was named the tournament's Most Valuable Player (MVP), headlining the All-Star Five Awards offered by Tissot. Mejri, who is recovering from a knee injury, was the MVP of Tunisia's title run in the 2011 AfroBasket.
Meanwhile, Fitzgerald and the Bulldogs scored 30 unanswered points against LSU's defensive depleted from injury and disqualification.
The Tigers' depth on both lines is a problem: Once LSU gets a little winded up front offensively and defensively, the dropoff in talent is dramatic.
In an early battle between two new coordinators, Mississippi State DC Todd Grantham won the chess match against more heralded LSU OC Matt Canada.
LSU hosts Syracuse in a nonconference game next Saturday.
Next, the Bulldogs will face another top 15 ranked team in Georgia in Athens.
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